Active Pharmaceutical Ingredients Baclofen CAS 1134-47-0 It is a GABA receptor agonist, specifically of the GABAB receptors. Its beneficial effects in spasticity result from actions at spinal and supraspinal sites. It is a derivative of γ-aminobutyric acid (GABA). A beneficial property of baclofen is that tolerance to its muscle-related therapeutic benefits does not seem to occur to a significant degree - baclofen retains its therapeutic anti-spasmodic effects even after many years of continued use. Newer studies, however, indicate that tolerance may develop in some people receiving intrathecal baclofen treatment. Active Pharmaceutical Ingredients Baclofen CAS 1134-47-0 It is a GABA receptor agonist, specifically of the GABAB receptors. Its beneficial effects in spasticity result from actions at spinal and supraspinal sites. It is a derivative of γ-aminobutyric acid (GABA). A beneficial property of baclofen is that tolerance to its muscle-related therapeutic benefits does not seem to occur to a significant degree - baclofen retains its therapeutic anti-spasmodic effects even after many years of continued use. Newer studies, however, indicate that tolerance may develop in some people receiving intrathecal baclofen treatment. Pet Massager,Cat Massage,Dog Massage,Pet Groomer Tools Shenzhen Jie Zhong Lian Investment Co., Ltd. , https://www.meizons.com
Quick Detail:
Product Name: Baclofen
Synonyms: β-p-Chlorophenyl-GABA
CAS: 1134-47-0
MF: C10H12ClNO2
MW: 213.66
EINECS: 214-486-9
Product Categories:Â Â Â Used as a skeletal muscle relaxation of the spinal cord
Mol File: 1134-47-0.mol
Description:
Baclofen is a white (or off-white) mostly odorless crystalline powder, with a molecular weight of 213.66 g/mol. It is slightly soluble in water, very slightly soluble in methanol, and insoluble in chloroform.
Baclofen is a medication used to treat spasticity. It is used as a central nervous system depressant and skeletal muscle relaxant. It is also used in topical creams to help with pain.
Chemically it is a derivative of the neurotransmitter γ-aminobutyric acid (GABA). It is believed to work by activating (or agonizing) GABA receptors, specifically the GABAB receptors. Its beneficial effects in spasticity result from its actions in the brain and spinal cord.
The drug is rapidly absorbed after oral administration and is widely distributed throughout the body. Biotransformation is low and the drug is predominantly excreted unchanged by the kidneys. The half life of baclofen is roughly 2-4 hours and it therefore needs to be administered frequently throughout the day to control spasticity appropriately.
Application:
Baclofen powder also known as β-(4-chlorophenyl)-γ-aminobutyric acid (β-(4-chlorophenyl)-GABA), used as a skeletal muscle relaxant. It is primarily used to treat spasticity. It is also used by compounding pharmacies in topical pain creams as a muscle relaxant.
Specifications:
Items Tested
Specification
Result
Characters
A white, crystalline powder or colorless crystals.
A white crystal.
Identification
IR should comply with the Reference Standard spectrum.
UV should comply with the Reference Standard spectrum.
An orange-red precipitate is performed.
IR complies with the Reference standard spectrum.
UV complies with the Reference standard spectrum.
An orange-red precipitate is performed.
Melting range
88 ~92 degree
89.8-90.2degree
Loss on Drying
Not more than 1.0%
0.22%
Readily carbonizable Substances
The resolution has no more color than Matching Fluid A.
Conform
Residue on ignition
Not more than 0.1%
0.02%
Heavy metals
Not more than 0.001%
Conform
Chloride
Conform
Conform
Assay (HPLC)
98.0%-102.0%
99.5%
Ordinary Impurities
≤1%
Conform
Reaction
Conform
Conform
Conclusion
Complies to USP31
Our adwantage:
1, High quality with competitive price:
  1) Standard: Enterprise Standard
  2) All Purity≥98%
  3) We are manufacturer and can provide high quality products with factory price.
2, Fast and safe delivery
  1) Parcel can be sent out within 24 hours after payment. Tracking number available
  2) Secure and discreet shipment. Various transportation methods for your choice.
  3) Customs pass rate ≥99%
  4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and    we have stock in there for transferring.
3, We have clients throughout the world.
  1) Professional service and rich experience make customers feel at ease, adequate stock and fast         delivery meet their desire.
  2) Market feedback and goods feedback will be appreciated, meeting customers's requirement is our       responsibility.
  3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the         customers.
Â
Quick Detail:
Product Name: Baclofen
Synonyms: β-p-Chlorophenyl-GABA
CAS: 1134-47-0
MF: C10H12ClNO2
MW: 213.66
EINECS: 214-486-9
Product Categories:Â Â Â Used as a skeletal muscle relaxation of the spinal cord
Mol File: 1134-47-0.mol
Description:
Baclofen is a white (or off-white) mostly odorless crystalline powder, with a molecular weight of 213.66 g/mol. It is slightly soluble in water, very slightly soluble in methanol, and insoluble in chloroform.
Baclofen is a medication used to treat spasticity. It is used as a central nervous system depressant and skeletal muscle relaxant. It is also used in topical creams to help with pain.
Chemically it is a derivative of the neurotransmitter γ-aminobutyric acid (GABA). It is believed to work by activating (or agonizing) GABA receptors, specifically the GABAB receptors. Its beneficial effects in spasticity result from its actions in the brain and spinal cord.
The drug is rapidly absorbed after oral administration and is widely distributed throughout the body. Biotransformation is low and the drug is predominantly excreted unchanged by the kidneys. The half life of baclofen is roughly 2-4 hours and it therefore needs to be administered frequently throughout the day to control spasticity appropriately.
Application:
Baclofen powder also known as β-(4-chlorophenyl)-γ-aminobutyric acid (β-(4-chlorophenyl)-GABA), used as a skeletal muscle relaxant. It is primarily used to treat spasticity. It is also used by compounding pharmacies in topical pain creams as a muscle relaxant.
Specifications:
Items Tested
Specification
Result
Characters
A white, crystalline powder or colorless crystals.
A white crystal.
Identification
IR should comply with the Reference Standard spectrum.
UV should comply with the Reference Standard spectrum.
An orange-red precipitate is performed.
IR complies with the Reference standard spectrum.
UV complies with the Reference standard spectrum.
An orange-red precipitate is performed.
Melting range
88 ~92 degree
89.8-90.2degree
Loss on Drying
Not more than 1.0%
0.22%
Readily carbonizable Substances
The resolution has no more color than Matching Fluid A.
Conform
Residue on ignition
Not more than 0.1%
0.02%
Heavy metals
Not more than 0.001%
Conform
Chloride
Conform
Conform
Assay (HPLC)
98.0%-102.0%
99.5%
Ordinary Impurities
≤1%
Conform
Reaction
Conform
Conform
Conclusion
Complies to USP31
Our adwantage:
1, High quality with competitive price:
  1) Standard: Enterprise Standard
  2) All Purity≥98%
  3) We are manufacturer and can provide high quality products with factory price.
2, Fast and safe delivery
  1) Parcel can be sent out within 24 hours after payment. Tracking number available
  2) Secure and discreet shipment. Various transportation methods for your choice.
  3) Customs pass rate ≥99%
  4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and    we have stock in there for transferring.
3, We have clients throughout the world.
  1) Professional service and rich experience make customers feel at ease, adequate stock and fast         delivery meet their desire.
  2) Market feedback and goods feedback will be appreciated, meeting customers's requirement is our       responsibility.
  3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the         customers.
Â
Active Pharmaceutical Ingredients Baclofen CAS 1134-47-0
Model NO.: 99%
CAS: 1134-47-0
Trademark: TJ
Transport Package: Camouflage Package
Specification: White powder
Origin: China
HS Code: 2937230090
Model NO.: 99%
CAS: 1134-47-0
Trademark: TJ
Transport Package: Camouflage Package
Specification: White powder
Origin: China
HS Code: 2937230090