Oral mucosal diseases such as oral lichen planus and recurrent blister can cause ulcer pain in the mouth, and the condition is difficult to control. Usually, doctors use steroid creams, ointments or mouthwashes to treat the affected area. The problem is that once administered, these drugs quickly spread throughout the mouth, which limits their exposure to the affected area and compromises the efficacy. Recently, British scientists have invented an "oral bandage" that delivers drugs to the mouth. The bandage can be applied directly to the inside of the mouth and adhere to the wound to better treat oral mucosal diseases.
Researchers at the University of Sheffield in the United Kingdom have teamed up with the Danish research team to develop the "oral bandage" called "Rivelin". It is made of nanofibers and is injected with the steroid clobetasol-17-propionate. The high-flexible patch has a non-toxic bio-adhesive on one side and a water-impermeable backing layer on the other side, which can continuously adhere to the moist part of the patient's mouth, and continuously releases drugs such as Steroids directly to the lesion without losing it. Other parts of the mouth.
In a laboratory test of 26 test subjects, the newly developed bandage was held in the patient's mouth for 2 hours, much longer than the duration of the ointment. It is reported that the patch will soon enter the clinical trial phase in the United Kingdom and the United States. â–² (Cai Lichao)
Steroids are a class of lipid soluble hormones. In the maintenance of life, regulating sexual function, body development, immune regulation, skin disease treatment and birth control has obvious effect. Steroid hormones are mainly used for: anti-inflammatory and anti-allergic; Treatment of male and female diseases and contraception; Improve metabolic function. Major side effects: more significant damage to the liver, and female masculinity. Long-term or a large number of use will appear acne, hairy, atrophic lines, purpura, osteoporosis, femoral head necrosis.
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