Release date: 2017-02-27 [Foreword] Tumor marker (TM) refers to a type of tumor cell that is characteristically present in tumor cells, or abnormally produced by tumor cells, or caused by the body's response to tumor stimulation, reflecting tumorigenesis, development, and monitoring tumor response to treatment. substance. Tumor markers are present in tissues, body fluids, and excretions of tumor patients and are currently detectable by immunological, biological, and chemical methods. Tumor patients encountered in clinical tumor marker tests were diagnosed with ovarian tumors at the age of 15 and have been treated with chemotherapy; those with rectal tumors in their 20s... encountered this in the test The situation is also not uncommon. Therefore, with the development of the economy and the improvement of medical standards, people's attention to health is also getting higher and higher. The detection of tumor markers is also common. However, the understanding of serum tumor markers and their clinical value cannot be effectively spread, but it causes some unnecessary anxiety. [Case] A patient with dysmenorrhea initially checked for tumor markers such as CA125. When the CA125 was 98 U/ml (reference value <35 U/ml), it was extremely urgent to seek assistance. I think I have a tumor in the reproductive system. After inquiry and appeasement, she was found to have undergone an examination during menstruation, and no abnormalities were found in imaging studies such as ultrasound.é‚ It is recommended to review it one week after menstruation. The review results are restored to the normal reference value. One tester, the whole family of four people detected CA724 results were higher than 100 + U / ml, the whole family gastroscopy and imaging examination were normal. Then ask carefully whether to take health care products or special food hobbies. Answer: I like to eat beans. After telling to stop using the beans for one month, the CA724 results were all normal. ã€case analysis】 From this point of view, there are many factors in the tumor marker test that will affect the test results. In addition to tumors, other diseases such as chronic infectious diseases, liver diseases, kidney diseases, diabetes, reproductive system diseases, benign gastrointestinal diseases, biliary diseases, etc., and in certain special circumstances, such as women's menstrual period and pregnancy ( CA125 detection value will be higher), male prostate massage and rectal examination (PSA detection value will be high), specimen hemolysis (NSE detection value will be high), taking certain drugs, will affect the detection results of serum tumor markers . Even a small number of normal healthy people will have high tumor markers. However, this situation is encountered during the detection process. Some tumor patients have negative tumor markers in their serum, such as alpha-fetoprotein in the serum of some patients with liver cancer. In response to such results, we generally need a combination of multiple related tumor markers combined with ultrasound imaging results, and even biopsy methods to further resolve the missed diagnosis and misdiagnosis of tumors caused by negative serum tumor markers. So can tumor markers not be used for tumor screening? The main tumor markers currently used for screening are alpha-fetoprotein (AFP) and prostate specific antigen (PSA). Both are suitable for screening for high-risk groups. The former mainly targets primary liver cancer, and the latter mainly targets screening of prostate cancer in middle-aged and elderly men. This also prompted us to work hard to find tumor markers with higher specificity, higher sensitivity, and more accurate organ directivity! ã€to sum up】 Tumor markers, literally, can be determined to have a certain relationship with tumors. Therefore, a positive tumor test report will cause anxiety and even panic. Therefore, as an inspection worker, the inspection should be taken seriously and responsibly. To understand the clinical application value and limitations of serum tumor markers, to understand the influencing factors of serum tumor markers before, during and after analysis, to regulate the use of serum tumor markers, in order to control this "sick" tumor markers! ! Source: Laboratory Medicine (Micro Signal Labweb) Many improper technical actions in sports are easy to cause knee joint injury. The fitting function of knee pad makes the knee joint stable during the movement, and wraps the lower end of quadriceps femoris, limiting the knee joint over-extension; The opening knee pad has a stronger restrictive effect, which greatly reduces the range of knee flexion and extension. Its good compression effect can effectively disperse the pressure on the knee and reduce the risk of sports injury.
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