Blood testing is widely used in disease diagnosis and drug efficacy monitoring because it is simple, convenient, cheap and fast. It is widely used in the fields of tumor diagnosis and prognosis, diagnosis of nervous system diseases, etc., and has made great contributions to the early diagnosis of tumors and other diseases. Below, Xiao Bian took stock of the recent research progress in blood testing and discussed it with everyone. 1. Nat Commun: Using liquid biopsy markers to detect prostate cancer invasiveness before surgery Recently, researchers from the University of Toronto in Canada have used non-invasive liquid biopsy methods to discover prostate cancer biomarkers that can help identify invasive prostate cancer before surgery. The study took four years and collected urine samples from approximately 300 patients, including prostate secretions, which were subjected to a digital rectal examination (DRE), a standard clinical test to determine if further prostate examination is needed. method. The researchers then used targeted proteomics to accurately quantify hundreds of proteins in the patient's urine samples and determine the distinct characteristics of the liquid biopsy. The first round of research included a total of 80 patients, and approximately 150 proteins were quantified, and the researchers further narrowed down the selection of 34 proteins for further study. The second round of research included a total of 210 patients. The researchers used computational biology methods to obtain quantitative biomarkers for invasive prostate cancer using quantitative data obtained from mass spectrometry. They plan to further expand the number of patient samples to verify whether these biomarkers they find have a broader clinical application in the field of prostate cancer. 2. New blood detection technology based on biochips can effectively detect Alzheimer's disease On the 68th American Association of Clinical Chemistry Annual Meeting and Clinical Laboratory Medical Equipment Fair (AACC Annual Meeting and Clinical Lab Expo ), researchers from the Long Road laboratory diagnosis, Ltd. (Randox Laboratories) said they have developed a new type of Blood testing technology can help identify high-risk Alzheimer's patients. This biochip-based blood test technology can perform multiple tests on a single blood sample, and it is currently using molecular biology techniques for analyzing DNA. Just as accurate and effective. The biochip-based blood detection technology developed by the researchers is able to detect proteins produced by the specifically mutated apolipoprotein gene (ApoE4) in the blood, and ApoE4 is directly related to the increased risk of Alzheimer's disease, and The gene can be inherited by parents, and when a patient inherits an ApoE4 mutant from a parent, the risk of developing Alzheimer's disease is tripled, and if the patient inherits from both parents (parents) ApoE4 mutants increase their risk of developing Alzheimer's disease by 8-12 fold. In order to verify the accuracy of this biochip detection technology, the researchers analyzed 384 samples and compared the results with the results of standard molecular diagnostic tests. The researchers collaborated with scientists at the Vienna Medical University and found that two The results of the tests are 100% consistent. This biochip detection technology allows many clinicians and researchers to perform multiple rapid tests on a single blood sample, and the technique is faster than standard DNA detection techniques (3) The results are low in time) and the price is low, which can help doctors quickly and accurately predict the risk of Alzheimer's disease in individuals. Insulin Syringes Needle,Disable Syringe,Monoject Syringe,10 Ml Syringe FOSHAN PHARMA CO., LTD. , https://www.foshanpharma.com
