Small magnets track cancer more sensitive and safer

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[China Pharmaceutical Network Technology News] Recently, a study published in the journal "ScientificReports" shows that the use of iron particles and magnetic probes can help clinicians accurately track the spread of lymph node tumors, which is more sensitive and safe than existing cancer monitoring methods. . However, the method is currently in the clinical pre-test phase, and researchers are working hard to develop it into clinical trials.

Life-saving surgery and treatment options rely on doctors' accurate tracking of cancer transmission. New devices for tracking cancer metastasis were invented by Aidan Cousins ​​of the University of South Australia and colleagues. For this invention, Aidan said, "The clinical pre-experiment of the new method confirms that iron particles and magnetic probes can very accurately determine the most likely tumors to spread, which will provide better health and prognosis for subsequent surgery and treatment. standard."

The iron particles used in this technique can be biodegraded at the primary site of the tumor (the primary site of the tumor as part of the monitoring), and the cells in the immune system can transport the biodegraded iron particles to the lymph nodes (primary cancer) It will initially spread to the lymph nodes). The injected iron particles will collect in the same position, and after 20 minutes of infusion, the researchers can use a magnet probe to detect their magnetic properties.

The network structure and nodes of the lymphatic vessels are notoriously difficult to draw structures. The only way to track the spread of cancer from the primary site to the lymph nodes is to have a radiotracer. In the new method, iron particles are injected into the patient and preferentially accumulate in the site where the tumor cells multiply, and the radiation probe can be used to determine the "hot spot" position. Aidan said, "The resolution of this method is about 20 mm. In addition, this method requires the patient to be exposed to a small amount of radioactive material." In contrast, Aidan developed magnetic technology to track the accuracy of cancer for patients and medical staff. Sex can be increased by a factor of 5 and is logically simpler and safer.

Aidan once again explained, “The most exciting part is the spatial resolution of the technology. Currently, we can use this technology to distinguish between benign and malignant from directly contacting lymph nodes. This means that patients can retain healthy lymph nodes and remove them. Cancerous lymph nodes to prevent further spread."

Aidan and colleagues hope to further improve the sensitivity of the technology, and improvements are also being researched, and they are working hard to develop the technology into clinical trials. According to Aidan, this method may be particularly suitable for identifying cancers that spread from the head and neck, and cancers that are transferred from the gastrointestinal tract can also be tracked by this method.

Dr. Melissa Moore, a clinical oncologist at St. Vincent's Hospital in Melbourne, Victoria, who has focused on breast cancer and lung cancer for many years, said: "The presence of cancer cells in lymph nodes is a key factor in determining cancer recurrence. We use the information from this node to guide Develop optimal treatment options for patients, including surgery, chemotherapy, and hormonal therapy. Aidan's approach has an important impact on clinical tracking of cancer spread."

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