Mayo Clinic teamed up with iSpecimen to create a domestic serum biobank

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The National Institutes of Health announced that it will provide $143 million for the Mayo Clinic in the next five years as a reward for the Biobank of the Obama Precision Medicine Initiative PMI project. Mayo Clinic said it plans to use the funds to collect, store and distribute biological samples to improve precision medical research. Recently, human biological sample supplier iSpecimen announced that it will work together as an exclusive channel partner for the Mayo Clinic to create a tumor/normal serum biobank.

What is a biological bank?

The biological bank is also called the biological sample library. It refers to a database that collects and stores biological samples for research (including tissues, serum, biological fluids, cells, etc.) and various clinical treatment data related to these samples. In medical research, it always plays an important role. All countries attach great importance to this and are actively creating more influential biological banks. Well-known British Biological Bank, American Union Medical Biobank and so on.

The Mayo Clinic Tumor/Normal Serum Bank is headquartered in Rochester, Minnesota, with a total of approximately 130,000 bottles of frozen serum and 17,000 special serum, all of which were taken with the patient's consent. The samples collected were between 1975 and 1990 and contained 85 different malignant or benign conditions. As a channel partner, iSPecimen will provide life science researchers with annotated biological samples, and manage inventory and related data through cloud technology to match biological sample information with research results.

Objective: To study individual differences and improve the level of precision medicine

With the advancement of precision medicine, the success of the cancer landing program and Parker's cancer immunotherapy, the research value of the Mayo Clinic's oncology/normal serum biobank is not only its large number, but also the longitudinal information of the sample itself. Similarly, the clinical annotation information of the sample is of great value, such as the patient's regional demographic characteristics, blood sample collection data, tumor information, treatment information, and tumor status of blood sample collection. These data can better help researchers understand the differences between individuals and find ways to personalize diagnosis and treatment.

Utilizing state-of-the-art technology and resource intensive management, the Mayo Clinic Biobank has created and collected a wide variety of human biological samples. “Although we hold thousands of samples of current hot research, these biological samples have not been used by researchers. iSPecimen has provided us with cooperation to provide higher quality and more diverse biological samples and more Complete sample information (such as lifestyle, health questionnaires, medical history, electronic health records, physical examinations and external environment, and real-time physiological conditions tracked using mobile health technologies) while saving researchers time and effort to learn more about inter-individual disease and health The difference.

Through cooperation, Mayo Clinic will establish a library of more biological samples to attract more people to register, better understand the differences between individual health diseases, and promote the development of precision medicine. Assuming 10,000 people sign up, the information collected will create an unprecedented database to better help researchers and researchers understand the factors. The more you know about individual differences, the more you can make more adjustments to the prevention and treatment of diseases based on differences, and improve the level of precision medicine.

Ultimately, Biobank will collect more than 350,000 biological samples and related data. The Mayo Clinic Florida Biological Access and Core Lab will hold 20% to 25% of biological samples, approximately 80,000 to 100,000. Dr. Thibodeau will also participate in the project to help guide the planning and action of the project.

Researchers believe that through the cooperation with iSpecimen, the field of influence of biobanks will expand from the scientific community in the field of medical research. It is estimated that in the next two decades, the number of new cancer cases worldwide will increase from 140,000 to 22 million per year. As tumor research continues to grow rapidly, researchers can find the right research methods faster, and high-quality biological samples will help them understand the core of new problems, diagnose them faster, and treat these diseases.

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