Because the discovery of hepatitis C is less than 30 years, there are no obvious symptoms in the early stage of the disease, and it is not included in the routine physical examination. Therefore, compared with hepatitis B, many people know little about the concept of hepatitis C, if not deliberately. To screen or inadvertently, because other medical examinations have been discovered, hepatitis C is easily missed and becomes a "time bomb" for the body that is ignored by the patient. In fact, as a "silent killer", hepatitis C has been listed as a common infectious disease in China and is seriously jeopardizing the health of Chinese people. It is understood that hepatitis C is caused by hepatitis C virus (HCV) infection, mainly transmitted by blood or body fluids. According to World Health Organization data, approximately 180 million people worldwide are infected with HCV, killing about 400,000 people each year. In China, the current anti-HCV positive rate of healthy people is 0.43%. In addition, high-risk groups such as occupational blood donation, hemodialysis, drug abuse, sexual disorder and other people, nearly 10 million people are suffering from hepatitis C threat. Due to various biological factors such as viral biological characteristics and host immune function, it is often difficult to effectively eliminate hepatitis C virus, so that about 50% to 80% of HCV-infected patients will develop chronic hepatitis, of which 20% to 30% will develop. Liver cirrhosis. And 1% to 4% of patients with cirrhosis develop into liver cancer every year. Although the current situation of hepatitis C is already very serious, the science and prevention of hepatitis C is still a major problem in the field of social public health. To this end, the author interviewed the director of the hepatitis C expert Wang Lei of the Second Hospital of Shandong University, and conducted a relevant understanding of the current status of hepatitis C treatment in China and the prevention and treatment of hepatitis C. The cure rate of hepatitis C treatment work has been greatly improved The development and progress of any thing must go through a long process, and the treatment of hepatitis C is no exception. According to Director Wang Lei, acute C is easily converted to chronic, chronic hepatitis C will continue to progress, can develop into cirrhosis, and even liver cancer, it should be actively antiviral treatment. Hepatitis C can be cured by anti-viral treatment. The treatment regimen is from the earliest common interferon to the common interferon plus ribavirin, to the pegylated interferon, which was once called "standard treatment". Baverin. However, this "standard treatment" method also has its limitations. The first cure rate is not too high. The domestic cure in China is still relatively high, reaching 70% to 80%, and 60% abroad. To about seventy; the second such treatment has its own many adverse reactions. Interferon-like causes patients with different degrees of fever, white blood cells and platelets, and may also cause some changes in thyroid function, and even some patients with decompensated liver function may even aggravate the condition after medication. So many negative effects will affect the clinical application of this treatment, and it is not suitable for patients with organ transplantation. Third, in the course of treatment and cost, the treatment course usually takes 24 weeks to 48 weeks, some patients Even 72 weeks are needed, and the treatment cycle is relatively long. In addition to the cost of drugs, patients must also be followed up frequently, so the cost is not too small. It is reported that since 2015, the so-called "standard treatment" program of pegylated interferon combined with ribavirin with lower cure rate and greater side effects has been no longer recommended in the European guidelines. With the introduction of more direct antiviral drugs for the treatment of hepatitis C, all interferon-containing regimens have disappeared from the guidelines since 2016. The domestic treatment program is also welcoming changes and renewals, and the treatment of hepatitis C has gradually entered the era of no interferon. From the birth of Sophob Buwei in 2013, in the treatment of hepatitis C, Gilead Science Company has experienced sophophos, "Ji II" Havani, "Ji San Dai" Bunda sand and just passed the US in 2017 The FDA-approved "Kiy 4" Vosevi drug iterative upgrade. This has brought new hopes for treatment to patients with hepatitis C. As the first pan-genotype of hepatitis C treatment, Bentongsha has also been approved by the State Drug Administration on May 23, 2018 for the treatment of genes in China. Adult infected patients with type 1-6 chronic hepatitis C virus (HCV). Director Wang Lei said that for the time being, the Gide sand produced by Gilead is the best drug for the treatment of hepatitis C virus. The most obvious advantage lies in its pan-genotype, various genotypes, mixed genotypes and unknowns. The genotype of hepatitis C virus treatment is effective; in the course of treatment, the therapeutic advantage of Bentham is also obvious, regardless of which hepatitis C virus genotype is infected, the treatment cycle is 12 weeks, even the more difficult to treat genes In type 3 patients, the treatment period is also 12 weeks, which is easy for the clinician to grasp; at the same time, it is also suitable for patients with decompensated cirrhosis, and the interaction with patients taking drugs due to other diseases is also less. Therefore, with the advantages of shorter course of treatment, better curative effect, fewer side effects and ease of use, Bunda sand is highly praised in the application of clinical drugs. However, the high price of Bentong sand has discouraged many patients. Director Wang Lei said that although the drug is effective, if it is not supported by medical insurance or with sufficient financial support, its use will be limited. When the doctor recommends the treatment plan for the patient, it will still be considered based on the patient's disease status and economic status. When talking about whether the future of Bentongsha will be included in medical insurance, Director Wang Lei said that Bundasha was included in the list of essential drugs by the state in September this year, which means that the efficacy, safety and necessity of the drug are obtained by the state. Accreditation, and whether it can be formally included in health insurance depends on many factors, such as depending on the country's financial resources and negotiations with manufacturers on price cuts; but in terms of the harmfulness of hepatitis C and good curability, Bunda sand is still the basic condition for being included in medical insurance drugs by the state. Director Wang Lei also said that in the promotion of special drugs such as Bentongsha, the drugs do not have to be stuck in the pharmacy of the hospital. If the general public can buy them at the pharmacy and enjoy medical insurance, it will greatly facilitate the treatment of patients. And with the rapid development of Internet medical platforms such as the Medical Association, doctors can conduct patient management and electronic prescription on the platform, which will save the doctor's time and energy to a certain extent, and improve the efficiency of patients' medical treatment. In addition, in February 2018, Gilead launched the “Up and Down Search, Healing Hepatitis B†project, supporting the China Primary Care Foundation to launch a patient rescue program to provide substantial relief for patients with hepatitis C in poor areas. Director Wang Lei believes that this move is very meaningful, and the Second Hospital of Shandong University is also one of the participants in this rescue plan, providing medical and medical assistance to poor patients. Understanding the route of transmission of hepatitis C to cure hepatitis C from the source of hepatitis C prevention When talking about the prevention of hepatitis C, Director Wang Lei said that because hepatitis C virus is extremely prone to mutation, and the protective neutralizing antibody of hepatitis C is still not particularly clear, the development of hepatitis C vaccine is very difficult and no less difficult than AIDS. . Therefore, to prevent hepatitis C, it is necessary to understand the route of transmission of hepatitis C. It is worth noting that general daily contact such as diet and breathing does not infect hepatitis C. Its transmission route is first through the spread of blood, followed by the spread of body fluids, such as unclean injections, acupuncture, sharing toothbrushes, Shaving razors, tattoos and beauty treatments in irregular beauty salons, infusions and tooth extractions in informal clinics, and sexual transmission and mother-to-child transmission. In 2014, the state also introduced relevant regulations requiring active screening for high-risk groups, such as those who lost blood or used blood products before 1995, drug users, dialysis or people who have been exposed to blood, or some Informal institutions who have done some medical and beauty projects such as eyebrows and sacred holes should take the initiative to screen for hepatitis C virus antibodies, so that early detection and early treatment can be done as long as they are treated in regular hospitals. Hepatitis can be cured. At the same time, hepatitis C is cured, and the source of infection is controlled from the source. In the prevention and treatment of hepatitis C, it is also necessary to cut off the route of transmission. Since nearly 20 years, China has implemented voluntary blood donation, abolished occupational blood donation and screening for hepatitis C. At present, it has basically eliminated the spread of hepatitis C in blood and blood products; in the medical process, we must continue to emphasize "one person, one use, one disinfection" and " One person, one needle and one tube; In mother-to-child transmission, before pregnancy, the mother must go to the screening of hepatitis C antibodies to prevent the occurrence of pregnancy. Finally, it is to protect susceptible populations and hopes to develop hepatitis C vaccine as soon as possible. At this stage, only by curing hepatitis C and cutting off the transmission route, it is possible to achieve a good vision of completely controlling hepatitis C in 2030. Another important function of amino acids is to provide energy to the human body. Normally, a healthy body on a general diet will use carbohydrates as its main fuel, but when the main source is depleted due to strenuous exercise, protein and amino acids can be used as a last resort. 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