Symptoms and prevention measures of porcine kidney disease

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Porcine kidney disease, also known as coronaria, is caused by the parasitic nematode parasitic in the pig's renal pelvis, kidney fat and ureter. The worms accidentally parasitize in the abdominal cavity and bladder. The disease is widely distributed, highly harmful, and often endemic, and is the main parasitic disease in pigs in tropical and subtropical areas.

猪肾虫病的症状和防治措施

Cause

The Duroc worm is stout, gray-brown, shaped like a matchstick, and its body wall is more transparent, and its internal organs are faintly visible. Males are 20-30 mm long, with small umbrellas and two crosses. The female is 30-45 mm long. The eggs are oblong, large, grayish white, blunt at both ends, thin eggshell, 99.8-120.8 microns long, and 56-63 microns wide.

2. Epidemiology

The eggs are excreted with the urine, and the first larvae are hatched after 1-2 days under suitable temperature and humidity conditions. After 2-3 days, the first larvae pass through the first and second molting and become the third. Larvae (ie, infectious larvae). Infectious larvae can infect pigs through two routes: one is oral infection and the other is transdermal infection. Oral infection is often caused by pigs swallowing infectious larvae; the larvae penetrate the stomach wall, remove the sheath, and after 3 days, the third epidermis becomes the fourth larva, and then enters the liver with blood flow. The skin-infected larvae penetrate into the skin and muscles and become the fourth stage larva in about 70 hours. The blood flows through the lungs and the big circulation into the liver. The larvae stay in the liver for 3 months or longer, passing through the envelope. Enter the abdominal cavity, then move to the kidney or ureter tissue to form a cyst, and develop into adult. A small number of larvae strayed into the spleen, spinal cord, psoas and other places, and could not develop into adult worms and die. From larvae invading pigs to developing into adults, it usually takes 6-12 months. The disease mostly occurs in the warm and rainy season of the climate. In the south of China, the pigs are infected more than 3-5 months and September-November. Infectious larvae are mostly distributed in the wall roots of pig houses and where pigs urinate, followed by wet places in the sports field. Pigs tend to ingest larvae when they dig in the wall, and when they lie down under the wall or in other damp places, the infectious larvae are infected by the skin.

猪肾虫病的症状和防治措施

3. Pathology

There are papules or nodules on the skin and the lymph nodes are swollen. There are cysts and abscesses in the liver, which contain larvae. The liver enlarges and becomes hard, the connective tissue proliferates, and the calcified nodules of the larvae can be seen on the cut surface. There is a thrombus in the hepatic portal vein, which contains larvae. There is abscess in the renal pelvis and connective tissue hyperplasia. The ureteral wall is thickened, and there are often a large number of cysts, which contain adult worms. Sometimes there are similar cysts around the bladder. There are more ascites in the abdominal cavity, and adults are seen. Nodules and abscesses can also be found in the pleura and lungs, and larvae can be found in the pus. In the sick pigs with hind limbs, larvae can be seen to compress the spinal cord.

Symptoms

Whether larvae or adults, the pathogenicity is very strong. When the larva penetrates into the skin, it often causes suppurative dermatitis, and the skin develops redness and small nodules, especially in the abdominal skin. At the same time, the lymph nodes on the body surface are often swollen. When larvae migrate in pigs, they can damage various tissues, with the lungs being the most seriously injured.

5. Diagnosis

Clinical observation, found that the back of the sick pig is weak and weak, hindquarters paralysis or unexplained claudication, urine can be microscopically detected, a large number of eggs can be found, can be diagnosed. Some people use the intradermal allergic reaction for early diagnosis, that is, the antigen is made by the adult of the kidney worm, and the concentration is 1:100, 0.1 ml is injected intradermally, and the result is checked after 5-15 minutes. The pimples at the injection site are larger than 1.5. The centimeter is positive; the diameter of 1.2-1.49 cm is suspicious; the less than 1.2 cm is negative.

猪肾虫病的症状和防治措施

6. Treatment

(1) Orthoimidazole. Intramuscular injection at 5-7 mg/kg body weight.

(2) albendazole. According to the weight of 20 mg / kg, a mixture of oral orally.

(3) Avermectin. Each 1 ml / 30 kg body weight, subcutaneous injection in the neck.

7. Control measures

It should be kept clean and dry inside and outside the circle, and the urination and drainage in the circle and the sports field should be smooth. The ground can be disinfected with lime water or 3-4 bleaching powder aqueous solution. Strengthen feed management, pay attention to feed mix, and give nutritious feed.

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