Release date: 2016-11-25 On the 23rd, I learned from the China Center for Disease Control and Prevention that the team of the Institute of Infectious Diseases, Zhang Yongzhen, made a major breakthrough in the study of the origin and evolution of the virus - the discovery of 1,445 new viral families, which greatly enriched the diversity of RNA viruses. And from the perspective of genetic evolution reveals the basic laws of RNA virus occurrence and evolution, some of which are so different from existing known viruses that they need to be redefined as new virus families. According to Zhang Yongzhen, the newly discovered viruses fill the major gaps in the evolution of RNA viruses and reveal a history of virus evolution characterized by host transformation and co-evolution. Collectively, these data present a more complex and genomic diversity of viral circles than the current taxonomic system, providing a more solid foundation for the ecological and evolutionary research of the virus. At the same time, this breakthrough has also changed the traditional concept of virology, providing a new foundation for understanding the evolution of the origin of life. RNA viruses are a type of biological virus. Among the common RNA viruses, the public is familiar and evasive, such as HIV, SARS, Ebola, and bird flu. It mutates rapidly during virus replication, so it is difficult to develop a vaccine. According to reports, the discovery of new viruses also reveals enormous flexibility in the viral genome, including frequent recombination, horizontal gene transfer between viruses and hosts, gene acquisition and loss, and complex genomic rearrangements. "Further analysis of the relationship between newly discovered viruses and known pathogens, revealing the law of its transmission and its pathogenicity to humans will help the prevention and control of new infectious diseases in China to achieve early recognition, early warning and precision. Prevention and control'. The detection and screening system of unknown viruses will also help to improve the clinical diagnosis ability of infectious diseases caused by unknown causes in China, and confirm the pathogens, so as to achieve targeted treatment." Zhang Yongzhen introduced. In the years of scientific research, the team performed macro-transcriptome sequencing on 9 animal gates and more than 220 invertebrate specimens. This sequencing is based on the total RNA of the microbial community in a particular sample. The composition of active species in microbial communities and their related conditions were analyzed at the transcriptional level. It is reported that the research results will be published in the world's top scientific journal Nature. In view of the significant biological significance of the research results, "Nature" headquarters decided to hold a press conference at 13 o'clock on the 23rd, US Eastern Time before the papers went online, to introduce this major achievement to the world. Source: Guangming.com - Guangming Daily
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