Release date: 2015-02-03 NextSeq 500 Sequencing System (Illumina) The world of life sciences is changing rapidly. The genome editing technology CRISPR has only just emerged in 2013. In the twinkling of an eye, there has been a whirlwind of CRISPR in the life sciences, with more than a thousand articles. The new technology platform takes research tools to new levels. Stand taller and have a chance to see farther. For the past 6 years, Biotech has been tracking the most cutting-edge innovations in the life sciences and introducing it to everyone. In 2014, Biotech continued to collect new products and offered a technical feast for everyone. After a one-and-a-half-month webpage and WeChat voting and expert evaluation, the 2014 Top Ten Innovations in Life Sciences were finally released. Among the award-winning products, there are brands we are familiar with, such as Illumina, Sigma-Aldrich and Bio-Rad. Their products have been continuously improved to achieve a wider range of applications; more are our strange names, such as Arraystar, TwistDx and Seahorse Bioscience, their novel products make experimentation simple, from slow to fast, and can't be done in the past. Of course, we also know that the work of the laboratory is quite heavy. I hope that you can stop in a hurry and not miss these beautiful scenery in the life sciences. Maybe, this will have a multiplier effect. NextSeq 500 Sequencing System (Illumina) The NextSeq 500 system turns high-throughput sequencing applications into everyday tools in laboratories around the world. With state-of-the-art SBS sequencing reagents, convenient touch screen operation and a smooth “sample-to-result†process, researchers can complete the hottest high-throughput sequencing applications in less than a day. CRISPR paired nicking enzyme (Sigma-Aldrich) This high-fidelity CRISPR technology is designed to reduce accidental off-target genetic modification. It creates a nick on the opposite two DNA strands to form a double-strand break. This design significantly reduces the likelihood of off-target while maintaining efficient and specific genetic modification. The new SNP genotyping platform---Juno system (Fluidigm) SNP genotyping (such as tissue, buccal swabs, blood, paraffin-embedded tissues, and polyploid organisms) that processed and completed DNA samples as low as 2.5 ng/ul in less than 3 hours, effectively breaking the gene The bottleneck field currently has bottlenecks for high concentration, high quality DNA requirements. Cicular RNA Microarrays (Human, Mouse) (Arraystar) Circular RNA (circRNA) is a newly reported class of regulatory non-coding RNA molecules with potential for clinical diagnostic markers. Arraystar is the world's first commercial circRNA chip. It utilizes specific splice site probe technology to accurately detect the expression changes of circRNA under different physiological and pathological conditions, and helps researchers systematically study this most novel ncRNA molecule. QX200 automatic micro-drop digital PCR system (Bio-Rad) In addition to adhering to the characteristics of QX100, QX200 system has newly added support for EvaGreen dye method, which makes it better compatible with quantitative PCR method and effectively reduces experimental cost. The introduction of the fully automatic model greatly simplifies the steps of droplet generation and realizes the concept of walk-away. P6-C4 New Sequencing Reagent (Pacific Biosciences) Pacific Biosciences upgraded the sequencing polymerase and chemical dyes (P6-C4) in late October 2014. The P6-C4 reagent can increase the average read length of PacBio to 10000 bp or longer, with >50% of sequence lengths exceeding 14,000 bp, and the longest read length > 40000 bp, which is far ahead in the industry. TwistAmp Nucleic Acid Amplification Product (TwistDx) Recombinase polymerase amplification (RPA) is considered to be a nucleic acid detection technology that can replace PCR. Based on this, the TwistAmp nucleic acid amplification product can perform single-molecule nucleic acid detection at room temperature within 15 minutes. It has high sensitivity and low equipment requirements, and is especially suitable for in vitro diagnostics, veterinary, food safety and other applications. Peggy Sue Microcellular Signaling Pathway Protein Quantitative Analysis System (ProteinSimple) As low as 25 cells, using nl samples for absolute quantification and post-translational modification of endogenous signaling pathway proteins, has been successfully applied to laser capture microdissection specific pathological cells, flow sorting of blood disease cells, fine needles Rare samples in clinical and basic research such as puncture samples. XFp Cell Energy Metabolism Detection System (Seahorse Bioscience) The miniaturization platform for the gold standard for cell energy metabolism detection, for the first time, perfectly transplants the extracellular flow detection technology to a platform that is more suitable for use in a small sample of individual laboratories, and adheres to consistent high-level detection results, thereby catalyzing the current hot energy metabolism. Detect more labs brought to all levels. XX Press quantitative PCR instrument (BJS Biotechnologies) The fastest quantitative PCR instrument in history. It uses a reaction plate as a resistive heating element to form an extremely low voltage circuit loop that delivers accurate heat directly. In addition, the thermal mass is extremely low, the heat transfer efficiency is high, and the temperature rise and fall speed of the whole cycle can reach 10 ° C / S, and 40 cycles of qPCR can be completed in 10 minutes. Source: Biopass
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2014 Life Sciences: Innovative Products Top10
On the list of the top 10 innovative products in the life sciences 2014, we have familiar brands such as Illumina, Sigma-Aldrich and Bio-Rad. Their products have been continuously improved to achieve a wider range of applications; more are our strange names. Such as Arraystar, TwistDx and Seahorse Bioscience, their novel products make experimentation simple, from slow to fast, to achieve the past can not.